IciStem is a collaborative project to guide and investigate the potential for HIV cure in HIV-infected patients requiring allogeneic stem cell transplantation for hematological disorders.
The IciStem consortium is composed of an expert European review panel of hematologists with experience in allogeneic SCT procedures along with infectious disease specialists, virologist and immunologists with expertise in the field of HIV-1 tropism, reservoirs and cure.
We prospectively study allogeneic SCT recipients with HIV-1 infection, collecting complete information on underlying malignancy, chemotherapy, transplant procedure, donor selection, HIV-tropism, cART, and virological and immunological characteristics of a variety of samples before and after the transplant.
IAS Cure Strategy
A new Cure strategy, developed by the International AIDS Society (IAS) was published on July 11th, 2016, in the journal Nature Medicine: http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4108.html
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ECCMID, 22 - 25 April 2017, Vienna, Austria
Title: Potential for HIV cure by stem cell transplantation; the IciStem project
Session Title: Cure for viral diseases
Presenter: Annemarie Wensing
Date: 23 Apr 2017
Session Time: 09:00 - 11:00
Session Hall: Hall A
Seminar "Reservorios e investigación básica sobre la curación del VIH", 27 April 2017, Barcelona, Spain
Title: Cell and Gene Therapy in HIV cure strategies
Presenter: Monique Nijhuis
UTRECHT/BARCELONA, October 3rd, 2016 - In response to the expanding international activities of the consortium, EpiStem, the European Project to guide and investigate the potential for HIV cure by Stem Cell Transplantation, announces its name change into IciStem,International Collaboration to guide and investigate the potential for HIV cure by Stem Cell Transplantation.
Over the last months patients from outside Europe have been included in the project. Following the press conference during the recent AIDS Conference in Durban, South Africa, the project receives a lot of international attention and exchange of information with several institutes from outside Europe has been reinforced.
As of September 12th, 2016, EpiStem will change its name into IciStem to better reflect the global nature of the project and the broader health care commitment. In alignment with the adoption of a new name, the website of the consortium is renamed into www.icistem.org.