International Collaboration to guide and investigate the potential for HIV cure by Stem Cell Transplantation


IciStem is a collaborative project to guide and investigate the potential for HIV cure in HIV-infected patients requiring allogeneic stem cell transplantation for hematological disorders.


The IciStem consortium is composed of an expert European review panel of hematologists with experience in allogeneic SCT procedures along with infectious disease specialists, virologist and immunologists with expertise in the field of HIV-1 tropism, reservoirs and cure.

We prospectively study allogeneic SCT recipients with HIV-1 infection, collecting complete information on underlying malignancy, chemotherapy, transplant procedure, donor selection, HIV-tropism, cART, and virological and immunological characteristics of a variety of samples before and after the transplant.


IAS Cure Strategy

A new Cure strategy, developed by the International AIDS Society (IAS) was published on July 11th, 2016, in the journal Nature Medicine: http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4108.html

Newsletter

If you want to be kept updated on the IciStem project, you can subscribe to the newsletter here.

NEWS

CROI Poster sessions 

Tuesday February 14th
Presentation: 2052- PERSISTENCE OF HIV DNA IN TISSUES EARLY AFTER TRANSPLANTATION WITH CCR5Δ32 STEM CELLS
Time: 2:30 PM - 4:00 PM
Presented During: EFFECT OF TRANSPLANTATION ON THE HIV RESERVOIR - P-E7
Location: Washington State Convention Center, Poster Hall - 4 E/F
Kobus Bosman1, Monique Nijhuis1, Anke Bruns1, Maria Salgado2, Gero Hütter3, Lodewijk Brosens1, Javier Martinez-Picado4, Jürgen Kuball1, Annemarie Wensing1
1University Medical Center Utrecht, Utrecht, Netherlands, 2AIDS Research Institute IrsiCaixa, Badalona, Spain, 3Cellex, Dresden, Germany, 4ICREA, Barcelona, Spain

Wednesday February 15th
Presentation: 1063 - MURINE MODEL TO PREDICT VIRAL REBOUND IN HIV+ ALLOTRANSPLANTED SUBJECTS
Type: Poster Session
Time: 2:30 PM - 4:00 PM
Presented During: LATENCY REVERSAL - P-E6
Location: Washington State Convention Center, Poster Hall - 4 E/F
Maria Salgado1, Mi Kwon2, Cristina Galvez Celada1, Monique Nijhuis3, Cristina Vilaplana4, Alessandra Bandera5, Annemarie Wensing3, Jose Luis Diez2, Javier Martinez-Picado1
1AIDS Research Institute, IrsiCaixa, Badalona, Spain, 2Hospital Gregorio Marañón, Madrid, Spain, 3University Medical Center Utrecht, Utrecht, Netherlands, 4Fundació Institut d’investigació en ciències de la salut Germans Trias i Pujol (IGTP), Badalona, Spain, 5San Gerardo Hospital - University of Milano-Bicocca, Monza, Italy


PRESS RELEASE
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The European project to investigate the potential for HIV cure by Stem Cell Transplantation adopts a new name to better reflect the international expansion of its activities

UTRECHT/BARCELONA, October 3rd, 2016 - In response to the expanding international activities of the consortium, EpiStem, the European Project to guide and investigate the potential for HIV cure by Stem Cell Transplantation, announces its name change into IciStem,International Collaboration to guide and investigate the potential for HIV cure by Stem Cell Transplantation.

Over the last months patients from outside Europe have been included in the project. Following the press conference during the recent AIDS Conference in Durban, South Africa, the project receives a lot of international attention and exchange of information with several institutes from outside Europe has been reinforced.

As of September 12th, 2016, EpiStem will change its name into IciStem to better reflect the global nature of the project and the broader health care commitment. In alignment with the adoption of a new name, the website of the consortium is renamed into www.icistem.org.

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The IciStem project is supported by AmfAR Research Consortium on HIV eradication (ARCHE) Research Grant # 109293-59-RGRL


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