International Collaboration to guide and investigate the potential for HIV cure by Stem Cell Transplantation


IciStem is a collaborative project to guide and investigate the potential for HIV cure in HIV-infected patients requiring allogeneic stem cell transplantation for hematological disorders.


The IciStem consortium is composed of an expert European review panel of hematologists with experience in allogeneic SCT procedures along with infectious disease specialists, virologist and immunologists with expertise in the field of HIV-1 tropism, reservoirs and cure.

We prospectively study allogeneic SCT recipients with HIV-1 infection, collecting complete information on underlying malignancy, chemotherapy, transplant procedure, donor selection, HIV-tropism, cART, and virological and immunological characteristics of a variety of samples before and after the transplant.


IAS Cure Strategy

A new Cure strategy, developed by the International AIDS Society (IAS) was published on July 11th, 2016, in the journal Nature Medicine: http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4108.html

Newsletter

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NEWS

Recent presentations

IAS HIV Cure & Cancer Forum, 22 & 23 July 2017, Paris, France
Oral presentation, title: Acheivement of full donor chimerism with episodes of alloreactivity contributes to reduce the HIV reservoir after allogeneic stem cell transplantation
Presentor: Maria Salgado
Date: July 23rd 2017

IAS HIV Cure & Cancer Forum, 22 & 23 July 2017, Paris, France
Poster, title: Murine model to predict viral rebound in HIV+ allotransplanted subjects
Presentor: Maria Salgado

9th IAS Conference on HIV Science, 23-26 July 2017, Paris, France
Poster, title: Allogeneic stem cell transplantation on HIV-1-infected individuals - the IciStem Consortium: the role of lymphocyte populations
Presentor: Maria Salgado

15th EU Meeting on HIV & Hepatitis, 7 - 9 June 2017, Rome, Italy
Oral presentation, title: HIV cure strategies
Presenter: Monique Nijhuis
Date: June 9th 2017
Session: 7

ECCMID, 22 - 25 April 2017, Vienna, Austria 
Oral presentation, title: Potential for HIV cure by stem cell transplantation; the IciStem project
Session Title: Cure for viral diseases
Presenter: Annemarie Wensing
Date: Arpil 23rd 2017
Session Time: 09:00 - 11:00
Session Hall: Hall A

Seminar "Reservorios e investigación básica sobre la curación del VIH", 27 April 2017, Barcelona, Spain
Oral presentation, title: Cell and Gene Therapy in HIV cure strategies
Presenter: Monique Nijhuis


PRESS RELEASE
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The European project to investigate the potential for HIV cure by Stem Cell Transplantation adopts a new name to better reflect the international expansion of its activities

UTRECHT/BARCELONA, October 3rd, 2016 - In response to the expanding international activities of the consortium, EpiStem, the European Project to guide and investigate the potential for HIV cure by Stem Cell Transplantation, announces its name change into IciStem,International Collaboration to guide and investigate the potential for HIV cure by Stem Cell Transplantation.

Over the last months patients from outside Europe have been included in the project. Following the press conference during the recent AIDS Conference in Durban, South Africa, the project receives a lot of international attention and exchange of information with several institutes from outside Europe has been reinforced.

As of September 12th, 2016, EpiStem will change its name into IciStem to better reflect the global nature of the project and the broader health care commitment. In alignment with the adoption of a new name, the website of the consortium is renamed into www.icistem.org.

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The IciStem project is supported by AmfAR Research Consortium on HIV eradication (ARCHE) Research Grant # 109293-59-RGRL


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